30 Apr, 2014The Microbiome in Drug Discovery: Metabolic Disease


In the “Age of the Microbiome” blog post which initiated this series we introduced the spectacular potential that the microbiome offers for drug…

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22 Apr, 2014The ABCs (and ATCGs) of RNA-Seq


DNA has often been likened to a book, with a set of instructions written in A’s, T’s, C’s, and G’s. But even if…

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04 Feb, 2014Sequencing and Drug Discovery: How does Illumina’s new $1000 human genome affect drug discovery?


Illumina recently announced the $1000 solution for the sequencing of the human genome in the form of its new instrument, the HiSeqX. This…

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15 Feb, 2013Next generation sequencing improved by genome mapping


Last month we ran a series of blog posts about next generation sequencing. Among the topics discussed were the limitations of next generation…

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04 Jan, 2013Next Generation Sequencing: Clinical Translation


Since the National Human Genome Research Institute (NHGRI) initiated a program in 2004 to advance sequencing technology development, the resulting next generation sequencing…

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02 Jan, 2013Next Generation Sequencing: Applications


Next generation sequencing has reduced costs and increased the throughput, as compared to Sanger sequencing. Importantly, it has expanded the capabilities of sequencing…

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28 Dec, 2012Next Generation Sequencing: Technologies


In the previous post, we saw the impetus behind the technological innovation that led to development of next generation sequencing. So, for aficionados, Dr…

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26 Dec, 2012Next Generation Sequencing: Necessity In The Age Of Genomics


This holiday season, while sipping eggnog and eating some delicious holiday treats, we invited Dr Sandeep Pingle, editor of Roundtable Review[1] to muse about…

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