25 Aug, 2014Drug Discovery Collapse: How to Fix Irreproducible Research?


Drug discovery, ever a challenge, can be likened to a tall structure. The upper stories rely on the stability of the floors below…

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04 Aug, 2014Children With a Rare Disease May Hold a Key to New Antivirals


Sometimes, in tragic circumstances, a lesson can be learned and applied in unexpected ways. That appears to be the case with a rare…

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28 Jul, 2014Crowdfunding of an HIV Vaccine Brings Hope and Skepticism


We have recently discussed here how crowdfunding — donations from the general public in support of a cause, idea, or invention — has…

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14 Jul, 2014CRISPR Marches Forward: Correcting a Disease in Animals


As we previously discussed, CRISPR-mania is sweeping the globe. (Okay, it might not be as big as Beatlemania, but more than a few…

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07 Jul, 2014Why Do Powerful Cancer Drugs Fail?


It’s a sad story that everyone is familiar with: A patient takes one or more well-known cancer drugs, and they work — for…

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23 Jun, 2014Human Genetics Lights the Way for Innovative Drug Discovery


The vast majority of compounds that enter clinical trials fail to make it through. The result: few drugs, plenty of bills. The consensus…

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05 Jun, 2014Fluorescent Tags: More Than Innocent Bystanders


A fluorescent tag, also known as a label or probe, is a molecule that is chemically attached to a biomolecule such as a…

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22 May, 2014ENABLE: Pushing Antibiotic Drug Discovery Forward


How difficult can antibiotic drug discovery be? Some of those struggling with their drug discovery projects in other areas might find themselves envying…

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15 May, 2014Driving Over the Drug Development Valley of Death


It’s a long, hard road that begins with the identification of a promising drug candidate and ends with its introduction to the marketplace….

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22 Apr, 2014The ABCs (and ATCGs) of RNA-Seq


DNA has often been likened to a book, with a set of instructions written in A’s, T’s, C’s, and G’s. But even if…

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