Biodegradable Long-Acting Injectable Implants Prepared By Hot Melt Extrusion

Date:

July 29, 2021

Time (ET):

11:00 AM

Duration (min):

Join Dr. Thanh Nguyen for a presentation on injectable implants developed using twin-screw extrusion, an upcoming technology in pharmaceutical manufacturing.

Injectable implants have distinct advantages for certain applications; for example, their efficacy over a long period of time can increase patient compliance, and the drug substance is applied in a non-systemic manner. Development and manufacturing of these implants often involves polymers as a matrix which makes twin-screw extrusion a perfect technology for their development. Nevertheless, it is a comparatively new technology and much can still be learned about the applicability and benefits of twin-screw extrusion. This seminar aims to give an introduction as well as real-life examples of what to look out for when entering this field of pharmaceutical manufacturing.

Who Should Attend?

Formulation scientists and engineers in the pharmaceutical industry
Academia who want to learn more about the possibilities to utilize HME for implant development and manufacturing

専門家の見解：

Thanh T. Nguyen

PhD

InnoCore Pharmaceuticals

Project Manager

スポンサー：

Thermo Fisher Scientific

コンテンツを探す

Thermo Fisher Scientific is the world leader in serving science. Their mission is to enable our customers to make the world healthier, cleaner, and safer. Through our Thermo Scientific, Applied Biosystems, and Invitrogen brands. They help customers accelerate innovation and enhance productivity.

https://www.thermofisher.com/sfn

トピック

Pharmacology

Biodegradable Long-Acting Injectable Implants Prepared By Hot Melt Extrusion

Who Should Attend?

専門家の見解：

Thanh T. Nguyen

PhD

スポンサー：

Thermo Fisher Scientific

トピック

関連コンテンツ

Advancing Metabolic Disease Drug Development: Translational Models and a GLP-1 Receptor Agonist Metabolism Case Study

Improving Translational Decision-Making through Disease-Relevant Preclinical Models in Pulmonary Fibrosis and Pain Drug Discovery

Smarter Drug Discovery: Turning Screening Hits into Opportunities

Smarter Drug Discovery: Turning Screening Hits into Opportunities

Improving Translational Decision-Making through Disease-Relevant Preclinical Models in Pulmonary Fibrosis and Pain Drug Discovery

Advancing Metabolic Disease Drug Development: Translational Models and a GLP-1 Receptor Agonist Metabolism Case Study

A More Complete Picture of Antibody Function: Lessons from Comprehensive Fc Profiling of Approved Anti-CD20 Antibodies

AI-Ready, Lab-Proven: A New Standard for High-Throughput Antibody Characterization

Enhancing Clinical Predictability through Human Disease-relevant Preclinical Models in CNS and Muscle Drug Discovery

Structure is Strategy: Integrating Cryo‑EM, X‑ray, NMR and HDX‑MS for Precision Drug Discovery

New Approach Methodologies (NAMs): Key Considerations and Applications

From Clinical Data to Actionable Assets for Pharmaceutical R&D

Strategies to Optimize Commercialization of Oncology Treatments for Younger Adults

Patient Data: Opportunities for Rare Diseases, Cell and Gene Therapies, and Oncology

Trials and tribulations of drug development

Webinar Series: Early patient preferences for patient-focused drug development

Looking Beyond Survival Data: Understanding the Value of Non-OS Endpoints in Oncology Reimbursement Decision-Making

Cutting Edge Conversations: Discovering New Innovations in Oncology

Detecting Early Synaptic Failure in Prion Disease Using Organoid Models

Improving Preclinical Decision-Making in Obesity and CKD with Translational In Vivo Phenotyping

Advancing the Manufacture of Mesenchymal Stromal Cells and Derived Extracellular Vesicles in Stirred-Tank Bioreactors Through Enhanced Bioprocess Control

How to Avoid Expensive Redesign Cycles in Antibody Discovery

From Genetic Validation to Relevant Target Engagement: Small Molecule Inhibitor Binding to 17β-HSD13

Bridging Mouse Models and Human Inflammatory Bowel Disease: in vivo Pharmacology, Histology and Biomarkers

Improving Confidence in Thyroid Hormone Disruption Assessment Using a Novel Human-Relevant In Vitro Model

Accelerating Antibody Discovery: Integrating Microfluidics, HT Expression, and Early Developability Platform

Beyond Exposure: Integrating PK/PD for Translational Predictive Power

Screening the Unscreenable: Expanding the Reach of Drug Discovery

Fulfilling the Gap: Innovative Critical Reagents for Non-Human Primate Preclinical Studies

Advancing ADC Development: Leveraging AI and Translational Preclinical Models to Improve Clinical Predictability

Human iPSC-Derived Sensory Neurons for Functional Sensory Biology and Pharmacology Research

From Biopsy to Better Decisions: Patient-Derived Organoids Predict Treatment Response in Metastatic Colorectal Cancer

Accelerating Conjugation Process Development for Next-Generation ADCs: Key Considerations and Platform Strategies

High-Throughput-qPCR and Transcriptomics: Powering the Next Generation of Drug Discovery

Epigenomics at 360 in Liquid Biopsy: Approaches and Case Studies for Biomarker Discovery and Drug Development

The Sound of Science: Mapping the Tumor Microenvironment for Advanced Therapeutic Strategies

Precision in Human Biological Samples: Leveraging Regulatory Rigor and Deep Data for Advanced Disease Research

Next-Generation TCR-Like Antibodies With Improved Specificity Profiles

ADC Payload-Linker CMC Process Development Strategy

De-Risking Immunotherapy Targets with Next-Gen HLA Discovery Platforms

Clinical Applications of Optical Cerebral Blood Flow Imaging

ADCs on The Horizon: The Performance and Prospect of Cell Line Development Platform AmigoCHO

Building New Approach Methodologies for Angiogenesis and Vascularized Models

Using ALS Patient-Derived Motor Neurons to Study TDP-43 Mislocalization

Vevo Ask The Experts: Oncology Imaging

hiPSC-Cardiomyocyte Platforms Enabling Comprehensive Cardiac Toxicity and Drug Efficacy Evaluation

Protein-Protein Interaction (PPI) Landscape - Sequence-to-Affinity Heatmaps for High-Throughput Antibody Optimization

Human Biological Samples in Research: Quality, Compliance, and Clinical Relevance

Combination Therapy for Glioblastoma: A Personalized, AI-Driven Approach

In Vivo panCAR Therapy Using Circular RNA for the Treatment of Autoimmune Disease

From Single Domain to Single B: Leveraging Biointron's Expertise for Antibody Discovery Success

Beyond Checkpoints: Strategic Use of CDX Models in Emerging IO Therapies

Non CYP Mediated Metabolism Pathways and In Vitro Evaluation Strategies

Uniting biology and digital drug discovery to identify new therapeutic opportunities in neurodegeneration

Enhance Your Tissue Processing Efficiency with the STEMprep Tissue Dissociator

Novel Applications of the Cellular Thermal Shift Assay (CETSA) Provide New Insights for Drug Discovery

Vaccine-Boosting CAR T Cells Against Solid Tumors

Exploring the iPSC-Derived Neuronal-Glia Co-culture System: A Powerful Drug Discovery Platform for Studying Neurodegenerative Diseases

Integrating Regulatory Guidance and Sustainable Skin Procurement for Consistent Execution of In Vitro Permeation Testing

Launch Event: Propelling Boundaries - Innovative Technologies in Early Drug Discovery

Advances in Preclinical Research using Human Co-culture Models: Applications in Immunology, Infectious Disease, and Oncology

Cell-Based Assays for Immuno-oncology

Artificial Intelligence in Preclinical Research: Pathology, Biospecimens, and Model Selection

CAR Finder - A Platform for Rapid CAR T Cell Screening

CRISPR Gene Editing in Primary T Cells: A Case Study in the Fight Against HIV

Improved Clearance Predictions for Aldehyde Oxidase Substrates Using TruVivo, a Novel Human Hepatocyte Model

Introduction to Bispecific Antibodies and Their Production

The Hidden Variable in Your Intestinal Organoids: Enhancing Differentiation for a More Predictive Model

Integrating Functionalized Multi-omics in Oncology Drug Discovery

Fresh or Cryopreserved Leukopaks? Assessing the Impact of Different Storage Conditions on Leukopak Stability

Breaking the Bottleneck: Harnessing Proteomics Services to Overcome Challenges in Clinical Research