Maximize Your Chances of Success: Avoid and Mitigate Risk of Failure When Developing Biotherapeutics

Advancing drug and vaccine candidates from late-stage discovery to clinical development requires navigating critical decision points under time and cost constraints while addressing developability, manufacturability, and immunogenicity challenges. Post-translational modifications, aggregation, and T-cell epitope risks must be carefully managed during this pivotal phase to ensure successful clinical progression.
Scientist.com
公開日
February 10, 2021

Date: March 10. Time: 4:00 PM CET.

Advancing your drug or vaccine candidate from late-stage discovery into the clinic is one of the most critical steps in development. This is the phase when you make key decisions that will have long-term scientific and business impact, frequently under extreme time and cost pressure. For example, developability and manufacturability issues can arise due to post-translational modifications and aggregation, and immunogenicity risks due to the presence of T-cell epitopes.

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Scientist.com
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