In this webinar, Dr. Peng reviews the current ADC landscape and share key considerations and platform strategies to accelerate conjugation process development for next-gen ADCs.
The bioconjugate landscape is evolving beyond traditional ADCs toward next generation ADCs such as bispecific ADCs and dual payload ADCs. While these modalities expand therapeutic potential, they also introduce more complex CMC requirements in conjugation process development, including tighter control of DAR profiles, intermediate stability, impurity clearance, and process scalability.
Using practical examples, the session covers how to design and optimize site-specific conjugation process, how to develop stepwise, in-process-control (IPC) strategies for dual-payload ADCs, and how to improve impurity control for novel payload linkers.
Presenters

Qiang Peng
Dr. Qiang Peng leads the conjugation process development team at AsymBio, with hands-on experience spanning both stochastic conjugation and advanced site-specific technologies.
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