The Future of Metabolic Phenotyping: Using data bandwidth to maximize N, analytical flexibility and reproducibility

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Sponsored by:

Sable Systems International Inc.
Date:
September 29, 2015
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An essential webinar for metabolic and behavioral researchers requiring detailed time courses and accurate correlation of energy expenditure and activity. We show the relevance of high-bandwidth metabolic measurement synchronized with intake and other behavioral data.

Methods matter. In metabolic measurement, confidence in reproducible results relies heavily on the design of the system used to acquire data. In the field of translational metabolic and behavioral phenotyping there is critical demand for more - throughput, standardization, synchronization of diverse data streams, temporal resolution, efficiency of workflow, and verification of results. We compare continuous and switched metabolic measurement methodologies and explore applications that benefit most from continuous measurement.

In this webinar sponsored by Sable Systems International, Dr. Jen Teske and Dr. John Lighton contrast methodologies and discuss how to improve best practices in metabolic phenotyping. They show how advances in high-bandwidth metabolic measurement, as implemented in Promethion metabolic phenotyping systems, leverage a 60- to 1200-fold increase in temporal resolution and achieve synchrony with intake and other behavioral data through the integration of telemetry.

Presenters

John Lighton

Sable Systems International
President and Chief Scientist

With a background in comparative and metabolic physiology and over 5,500 citations, John Lighton, is a self-proclaimed ‘recovering academic’, still affiliated with the University of Las Vegas. He juggles ongoing research with the development of advanced, blazing-fast metabolic and behavioral phenotyping systems designed from the perspective of a scientist rather than an engineer, emphasizing consummate analytical flexibility.

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Jennifer A. Teske

University of Arizona (Department of Nutritional Sciences)
Assistant Professor

Dr. Jennifer Teske studies the neural mechanisms and dietary factors regulating weight gain associated with abnormal sleep in rodent models. While her primary goal is to quantify the energetic cost and temporal relationship between bouts of sleep, physical activity and feeding, establishing the therapeutic efficacy of centrally administered orexin on body weight gain is paramount. These studies are performed by concurrently measuring sleep, physical activity, feeding and energy expenditure in free-living rodents in vivo with DSI’s F40-EET telemetry implant among other metabolic research tools.

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Sponsor

Sable Systems International Inc.

Sable Systems International contributes to the research community with superior instrumentation and software for innovation and discovery. Their metabolic phenotyping systems measure calorimetry, respirometry, metabolic/behavioral phenotyping and gas analysis at the best possible resolution and precision, providing unprecedented analytical and statistical power.

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