Applied Pathology Systems (APS) is a CLIA-certified histopathology contract research organization (CRO) based in Shrewsbury, MA, supporting pharmaceutical, biotech, and academic research institutions worldwide.
Our Services:
🔬General Histology: Tissue processing, embedding, sectioning, and H&E staining
🧫 Immunohistochemistry (IHC): High-quality IHC staining, multiplex IF, and antibody screening
🧬 RNAscope (ISH): Highly specific RNA in situ hybridization for gene expression and gene therapy research
🗺️ Spatial Biology: Spatial phenotyping and multiplex tissue profiling for immuno-oncology research
🎨 Special Staining: Full range of histology special stains (Masson's Trichrome, PAS, Alcian Blue, VVG, and more)
📷 Digital Pathology Imaging: Whole slide scanning, brightfield and fluorescence, with secure cloud access
📊 Image Analysis: Quantitative IHC and IF image analysis, cellular and subcellular quantification
📋 Pathology Reporting: Expert tissue scoring and regulatory-ready histopathology reports
🏥 Surgical Pathology: CLIA-certified subspecialized pathology reports for clinical and research use
🧪 TMA Construction: Custom tissue microarray building for high-throughput IHC and ISH studies
🩺 Clinical Trials & Studies: Full histopathology support from study design to regulatory-ready reporting
📦 Human Specimens & Control Slides: Validated FFPE human tissue sections with annotated clinical data
