How to Create CRISPR-Edited T Cells More Efficiently for Tomorrow's Cell Therapies

Sponsored by:

Date:

May 18, 2023

Time (PT):

2:00 PM

Duration (min):

No items found.

Steven Loo-Yong-Kee presents Artisan Bio's STAR-CRISPR system for optimized gene editing in cell therapy, with a focus on the genetifc modification of T cells for cancer immunotherapy.

Cell therapy is an emerging field with great promise for the treatment of various diseases. One of the most exciting areas of cell therapy is the use of T cells that have been genetically modified to recognize and kill cancer cells. While the use of T cells for cancer immunotherapy has tremendous promise, there is still room for improvement. The efficiency, expansion, and functionality of T cells can be enhanced by genetic modification using the STAR-CRISPR system.

Artisan Bio is a biotechnology company focused on developing a CRISPR-mediated editing platform to improve the efficacy and safety of cell therapy products. In this webinar, we will provide a comprehensive overview of Artisan Bio's STAR-CRISPR system, which is designed to improve the specificity and efficiency of gene editing for cell therapies. We will explain the system's key components and how we are using a risk-based approach to optimize and validate the editing platform. The webinar will focus on Artisan Bio's approach to building T cell OS/APPS through iterative improvements to achieve best-in-class editing capabilities and improved cell health metrics.

Presenters

Steven Loo-Yong-Kee

Artisan Bio (Cell Biology and Immunology)

Scientist II

Steven is a chemical engineer with over 7 years of experience in the cell and gene therapy industry, specializing in immunotherapy products. He has played a critical role in the development of Artisan's T cell and iPSC editing platforms, including process development, optimization, and technology transfer. He is also a founding member of the company's internal DoE core, offering insights into QbD methodologies.

STEMCELL Technologies Inc.

STEMCELL Technologies develops specialty cell culture media, cell isolation products and accessory reagents for life science research. Generate hPSC-derived cerebral organoids for a physiologically relevant in vitro model system with the STEMdiff Cerebral Organoid Kit. Use BrainPhys Neuronal Medium to culture active hPSC- and primary tissue-derived neurons in a physiological environment. The NeuroCult product line for primary and CNS-derived neural stem cells includes 30+ media and supplements, culture assays and differentiation kits. For human neurological disease modeling, the STEMdiff Neural System supports every step in your iPS-neural workflow, from neural induction to downstream differentiation.

Topics

Pharmacology

Cell Culture & Characterization

DNA & RNA

How to Create CRISPR-Edited T Cells More Efficiently for Tomorrow's Cell Therapies

Presenters

Steven Loo-Yong-Kee

Sponsor

STEMCELL Technologies Inc.

Topics

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