Improving Confidence in Thyroid Hormone Disruption Assessment Using a Novel Human-Relevant In Vitro Model

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Sponsored by:

LifeNet Health LifeSciences
Date:
May 7, 2026
Time (ET):
11:00 AM
Duration (min):
60

Learn how an emerging NAM is helping advance more efficient, human-relevant strategies for assessing thyroid hormone disruption while reducing reliance on animal testing.

Endocrine-disrupting chemicals present a growing global health concern, with the potential to interfere with critical hormonal systems such as thyroid function. However, current approaches to evaluating thyroid toxicity often rely on resource-intensive animal studies or in vitro methods that do not fully capture human-relevant biology.

In this webinar, Chad Deisenroth introduces advances in a new approach method (NAM) for thyroid toxicity testing, with a focus on a human-relevant in vitro model (Human 3D Thyroid Microtissue) that enables direct assessment of thyroid hormone synthesis.

Attendees will gain insight into how this model addresses key limitations in traditional testing strategies by improving biological relevance, reproducibility, and scalability. The session also highlights how recent validation efforts have strengthened confidence in this approach, supporting its application in screening workflows for endocrine-disrupting chemicals.

Presenters

Chad Deisenroth

UL Research Institutes' Chemical Insights (Center for Chemical Informatics and Screening)
Principal Laboratory Toxicologist

Dr. Chad Deisenroth is a Principal Laboratory Toxicologist in the Center for Chemical Informatics and Screening at UL Research Institutes' Chemical Insights. He earned his Ph.D. in Genetics and Molecular Biology from the University of North Carolina at Chapel Hill and completed postdoctoral training in chemical safety sciences at The Hamner Institutes for Health Sciences.

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Sponsor

LifeNet Health LifeSciences

LifeNet Health LifeSciences leads the way in human in vitro biology for both non-diseased and diseased research needs. LifeNet Health LifeSciences combines innovative, technology-driven research and development programs to create human tissue and cell-based research products and services.

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