Webinar Summary
- Development of the 3D thyroid microtissue model.
- Evaluation of model performance, including the production of thyroid hormone.
- Standardization of the model for thyroid disruption testing.
In this webinar, Dr. Deisenroth discusses the US EPA Endocrine Disruptor Screening Program's (EDSP) approach to screen chemicals for potential thyroid-disrupting effects and the urgent need to advance new approach methods that protect human health while reducing animal testing. He showcases how hormone production in the model mimics human endocrine biology and is inhibited following exposure to known reference chemicals that affect key targets within the thyroid gland.
Dr. Deisenroth also explains the methodology behind establishing minimum donor qualification criteria and benchmark parameters for test method standardization, transferability, and validation. This approach balances performance standardization with the ability to predict a range of human responses.
Lindsey Whaley from LifeNet Health then unveils the first primary human thyrocyte product that enables access to the 3D thyroid microtissue model. Join us for a journey into cutting-edge scientific research that promises to reshape how we assess thyroid disruption.
Presenters
Chad Deisenroth
Dr. Chad Deisenroth is a Principal Laboratory Toxicologist in the Center for Chemical Informatics and Screening at UL Research Institutes' Chemical Insights. He earned his Ph.D. in Genetics and Molecular Biology from the University of North Carolina at Chapel Hill and completed postdoctoral training in chemical safety sciences at The Hamner Institutes for Health Sciences.
Lindsey Whaley
As LifeSciences product manager, Lindsey has a passion for driving innovation and delivering exceptional user experiences. Known for her collaborative approach and ability to translate marketing insights into actionable strategies, Lindsey is dedicated to delivering products that align with core customer needs. Lindsey holds a bachelor’s degree in biology and a master’s degree in biotechnology. During her academic journey, she completed two internships at LifeNet Health focused on various LifeSciences marketing projects where she quickly developed a passion for making high-quality, human research solutions accessible to scientific researchers. In her role as Product Manager for LifeNet Health LifeSciences, Lindsey collaborates with cross-functional teams to manage new product releases and an existing portfolio to a global market. She most enjoys using her scientific background to effectively communicate the benefits of LifeSciences’ innovation portfolio to the scientific community.
Sponsor
LifeNet Health LifeSciences
Content Partners
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