Join AbbVie scientists Shitalben Patel and Jami R. Erickson as they showcase their innovative advancements, transforming CETSA into a high-throughput flow-based platform and introducing new whole blood formats to elevate drug discovery.
In this webinar, you'll learn about flow-based CETSA, a powerful, high-throughput technique that enables single-cell target engagement analysis without cell lysis. Designed for screening of large compound libraries, this method overcomes traditional limitations like low throughput and high cell input. You will also hear how the method is being integrated into real-world SAR funnels to accelerate hit generation.
In the second half of the webinar, you will learn about novel Alpha and MSD CETSA formats for whole blood, using RIPK1 as a proof-of-concept. These assays require <100 μL of blood, eliminate PBMC isolation, and deliver clinically relevant, reproducible readouts—bringing true target engagement measurement closer to patient-derived samples.
Don't miss this opportunity to explore how these CETSA innovations can transform your approach to drug discovery—from high-throughput screening to clinical translation.
All intellectual property rights, including copyrights and trademarks, relating to CETSA are owned by Pelago Bioscience AB.
Presenters
Shitalben Patel
Shitalben Patel is a Scientist in the chemical biology group at AbbVie. Her role involves developing high-throughput chemoproteomics workflows, employing chemical biology technologies to understand drug-target engagement, on and off-target selectivity profiling, as well as mechanism-of-action for small molecule drug discovery.
Jami R. Erickson
Dr. Jami R. Erickson is a Senior Scientist in the molecular screening and characterization group at AbbVie in North Chicago. Her work focuses on high-throughput screening and innovative technique development, including the pioneering of flow-based CETSA techniques.
Sponsor
Pelago Bioscience
Content Partners
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