Sponsored by:

Alloy Therapeutics

Beyond Affinity: Multi-Parameter Optimization of Multispecific Building Blocks

Date:
October 28, 2026
Time (ET):
11:00 AM
Duration (min):
60
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Alloy Therapeutics
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A promising antibody building block may have the affinity you want while carrying potential developability liabilities that limit its use in a multispecific format. Addressing those liabilities without compromising the properties that made the molecule valuable requires optimization across multiple parameters.

Join Alloy scientist Dalton Markrush to explore a rapid, multi-parameter approach that integrates in vitro and in silico workflows to evaluate and optimize developability alongside affinity.

In this webinar, attendees will learn how Alloy:

  • Evaluates developability alongside affinity in multispecific building blocks
  • Integrates in vitro and in silico workflows for rapid, multi-parameter optimization
  • Improves limiting properties while monitoring favorable starting characteristics
  • Applies these approaches in practice through representative case studies

Featuring Insights from

Dalton Markrush

,

MS

Alloy Therapeutics
Associate Director, Protein Analytics

Dalton Markrush, Associate Director of Protein Analytics at Alloy Therapeutics, develops methods and workflows to accelerate early- and late-stage antibody developability for partner programs. Prior to joining Alloy, Dalton worked on protein analytics and binding at Compass Therapeutics. He holds a master’s degree in biotechnology from Northeastern University.

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Sponsored by

Alloy Therapeutics

Alloy Therapeutics is a Product Development Organization supporting partners in the discovery, development, and commercialization of therapeutic drug programs. Alloy provides AI-powered biotechnology infrastructure through proprietary technology platforms, integrated services, and company creation—with no competing internal drug pipeline.
https://alloytx.com/

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