Join Dr. Alexandra Lubin and Dr. Jason Otterstrom as they discuss the use of deep learning-powered automated microscopy and image analysis for fast, in vivo zebrafish screening.
To watch this webinar, please contact IDEA Bio-Medical: info@idea-bio.com.
Zebrafish are rapidly becoming a popular model organism for in vivo studies, particularly for drug screening and toxicology studies. Their benefits include fast development, economical husbandry, and direct amenability to microscopy since embryos are transparent. While imaging is fairly straightforward, in many cases, a substantial bottleneck to automated workflows is image analysis.
In this webinar, Dr. Jason Otterstrom and Dr. Alexandra Lubin describe an AI-powered analysis platform developed to enable true high-content screening of zebrafish, and highlight a range of applications where they have validated its performance. In brief, the easy-to-use software automatically identifies the fish outline, and internal anatomy & body regions with no required user inputs. They demonstrate the platform's applicability in the context of counting GFP-labeled hematopoietic stem cells specifically in the tail region, along with measurement of x-ray induced apoptosis and dual-color analysis.
Who Should Attend?
- Researchers using zebrafish and microscopy in their work
- Researchers looking for a model organism to do in vivo toxicology or drug screening
- People interested in automated screening of whole organisms
Presenters
Jason Otterstrom
Dr. Otterstrom is an application scientist for IDEA Bio-Medical. He has a diverse background in biophysics including microscopy, optical design, image analysis and sample labeling. His expertise is adapting biological assays to benefit from utilization of automated microscopy methods.
Alexandra Lubin
Dr. Lubin is a post-doc at the UCL Cancer Institute where she uses zebrafish to study myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML), aiming to develop novel therapeutic treatments. Previously, she obtained her PhD in Chemical Biology from Imperial College London after studying Chemistry at the University of Cambridge.
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