Fully Characterized, Standardized Human Induced Pluripotent Stem Cell Line and Ready-to-Use, High-Quality Neural Progenitor Cells for Downstream Differentiation Applications

Sponsored by:

Date:

June 29, 2023

Time (PT):

11:00 AM

Duration (min):

In this webinar, experts present a standardized stem cell line and its differentiation into neural cells for disease modeling and assay development.

Reproducible research with human induced pluripotent stem cells (iPSCs) depends on thoroughly characterized and quality-controlled cell lines. In this webinar, Dr. Andrew Gaffney and Dr. Erin Knock from STEMCELL Technologies describe the generation of a standardized induced pluripotent stem cell (iPSC) line. Developed with the upcoming ISSCR Standards Initiative characterization guidelines in mind, this highly characterized line is karyotypically stable, demonstrates trilineage differentiation potential, and expresses undifferentiated cell markers. Further, STEMCELL has developed a highly pure, ready-to-use neural progenitor cell product expressing PAX6 and SOX1 over multiple passages.

Dr. Knock shows how these multipotent cells are suitable for customized downstream differentiation to various CNS cell types, such as forebrain neurons, midbrain neurons, and astrocytes. These progenitor cells are the ideal controls for standardizing downstream differentiation protocols, modeling diseases, and assay development.

Presenters

Andrew Gaffney

STEMCELL Technologies (Business Operations)

Director, Stem Cell Manufacturing and Commercialization

Dr. Andrew Gaffney is the Director of Stem Cell Manufacturing and Commercialization at STEMCELL Technologies, overseeing the development of iPSCs, differentiated cells, and organoids. He also develops strategic alliances with stem cell scientists to support the development of PSC-based disease models, drug screens, and cell therapy applications.

Erin Knock

STEMCELL Technologies (Research & Development)

Associate Director, Neural Biology

Dr. Erin Knock is the Associate Director of Neural Biology in the Research and Development Department at STEMCELL Technologies. Erin and the Neuroscience Group are proud to support products for both primary neural culture and pluripotent stem cell differentiation, including organoid differentiation.

STEMCELL Technologies Inc.

STEMCELL Technologies develops specialty cell culture media, cell isolation products and accessory reagents for life science research. Generate hPSC-derived cerebral organoids for a physiologically relevant in vitro model system with the STEMdiff Cerebral Organoid Kit. Use BrainPhys Neuronal Medium to culture active hPSC- and primary tissue-derived neurons in a physiological environment. The NeuroCult product line for primary and CNS-derived neural stem cells includes 30+ media and supplements, culture assays and differentiation kits. For human neurological disease modeling, the STEMdiff Neural System supports every step in your iPS-neural workflow, from neural induction to downstream differentiation.

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Topics

Cell Culture & Characterization

Pharmacology

Fully Characterized, Standardized Human Induced Pluripotent Stem Cell Line and Ready-to-Use, High-Quality Neural Progenitor Cells for Downstream Differentiation Applications

Presenters

Andrew Gaffney

Erin Knock

Sponsor

STEMCELL Technologies Inc.

Content Partners

Scientist.com

Topics

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