Webinar Summary
- Why organoids? - Advancements and alternative models to support the 3R's (replace, reduce, refine) of animal models
- How did we get here? - Understand the challenges of 2D electrodes and the introduction of the 3D Mesh MEA
- Benefits of the platform - Electrophysiology simplified…simple integration and flexibility using a universal, well-established platform
- It's all possible - Cell culture, slices, organoids, implantation, and beyond
In today's fast paced research environment, drug testing, regulatory requirements, and alternative methods are at the forefront of neuroscience research. In this webinar, Dr. Sven Schönecker discusses the latest in 3D Mesh MEA's, its ability for a more true-to-life system for studying organoids, and the versatility of the well-established MEA2100 system from Multi Channel Systems (MCS), an affiliate of Harvard Bioscience (HB).
The main challenge in the brain organoid field is to monitor neural network formation within development and manipulate the synaptic plasticity of mature brain organoids. Indeed, this challenge hinders neuroscientists from achieving all aspects of human brain-on-chip. In this webinar, Sara talks about how growing brain organoids around the electrodes, using Mesh MEA, brings neuroscientists closer to the brain-on-chip inherence.
Presenters
Sven Schönecker
Sven is a Sr. Application Scientist, the Application Team Leader for Cellular and Molecular Technologies in EIMEA, and is now the global Product Manager for Multielectrode Arrays (MEA) at Multi Channel Systems.
Sara Mirsadeghi
Sara studies the electrophysiological properties of different brain organoids, derived from healthy donors as well as patients with congenital epilepsy, employing standard MEAs, 3D-MEAs and newer Mesh-MEAs.
Sponsor
Harvard Bioscience, Inc.
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