Disease Models

Tumor Tissue Microarrays (TMAs): A High-Throughput Engine for Cancer Research

Industry Insights with Henry Zhu and BPS Bioscience

Understanding Biological Material Licensing for Preclinical Research

Fibrosis Disease: From Mechanisms and Therapeutic Targets to Animal Models

Talking Real Science with Yelena Akelina

The Year in Review: Biotherapeutics in 2024 and a Look Ahead to 2025

Engineering Neuromodulation for Cardiovascular Instability

Improving Preclinical Decision-Making in Obesity and CKD with Translational In Vivo Phenotyping

Detecting Early Synaptic Failure in Prion Disease Using Organoid Models

Skeletal Muscle Circadian Clocks: Keeping Time for Systemic Health

Functional Ultrasound Demonstration and Live Q&A: Iconeus One, a Pioneer in Real-Time Whole-Brain Imaging

Bridging Mouse Models and Human Inflammatory Bowel Disease: in vivo Pharmacology, Histology and Biomarkers

Illuminating the Brain: Advances in Neurobiology

Fulfilling the Gap: Innovative Critical Reagents for Non-Human Primate Preclinical Studies

Advancing ADC Development: Leveraging AI and Translational Preclinical Models to Improve Clinical Predictability

Precision in Human Biological Samples: Leveraging Regulatory Rigor and Deep Data for Advanced Disease Research

Opening a New Window: Stable Long-Term Imaging of Dura Mater-Transplanted Pancreatic Islets in Awake Mice

The Expert Approach to Preclinical Indirect Calorimetry Experiments

Photoreceptor Cell Therapy to Treat Advanced Retinal Degeneration

Clinical Applications of Optical Cerebral Blood Flow Imaging

Using ALS Patient-Derived Motor Neurons to Study TDP-43 Mislocalization

Gene-Agnostic Gene Therapy to Preserve Vision

Vevo Ask The Experts: Oncology Imaging

hiPSC-Cardiomyocyte Platforms Enabling Comprehensive Cardiac Toxicity and Drug Efficacy Evaluation

Noninvasive Imaging of Liver Disease by MRI and Photoacoustic Ultrasound

Transcranial Focused Ultrasound Neuromodulation of the Default Mode Network in the Treatment of Depression and Promotion of Wellness

In Vivo panCAR Therapy Using Circular RNA for the Treatment of Autoimmune Disease

FUJIFILM VisualSonics' Advanced Cardio Symposium

Recent Advances in Diagnosis of Autonomic Syncope

Scent-sational Solutions: Odour Delivery and Validation with Aurora Scientific's Olfactometer and miniPID

Uniting biology and digital drug discovery to identify new therapeutic opportunities in neurodegeneration

Exploring the iPSC-Derived Neuronal-Glia Co-culture System: A Powerful Drug Discovery Platform for Studying Neurodegenerative Diseases

Setup and Use of the 3-in-1 Whole Animal System

Redox Regulation of Skeletal Muscle: A Journey from Liverpool to the International Space Station

Advances in Preclinical Research using Human Co-culture Models: Applications in Immunology, Infectious Disease, and Oncology

Reprogramming Mouse Fibroblasts Into Induced Cardiomyocytes: Age-Related, Metabolic, and Epigenetic Barriers

RIP1 Inhibition Protects Retinal Ganglion Cells in Preclinical Glaucoma Models

Animal Welfare in Surgery: Then and Now

The Trainer's Toolkit for Osmotic Pumps: Supporting Researchers in Infusion Studies

Leveraging Genomic, Preclinical, and Drug Response Data in the Age of AI

High-Resolution Intravital In Vivo Imaging with AI-Powered Image Denoising

Iconeus One: Pioneering Real-Time Whole-Brain Imaging with Functional Ultrasound - 14 Years of Innovation and Adoption

Exciting Expansion in Preclinical Photoacoustic Imaging with VisualSonics Technology

Aging and Injured Retinal Ganglion Cells can be Rejuvenated by Epigenetic Reprogramming

Hypertension and Hypothalamic Changes in a Mouse Model of Menopause

New Treatments for Vasomotor Symptoms Due to Menopause

Migraine: Past, Present, and Future

An Advancement in Pressure-Volume Technology: Meet the Millar MPVS Duo

Polycystic Ovarian Syndrome and Cardiovascular Disease

The Impact of Lateral Inhibition on Healthy Vision and Retinal Degeneration

Revolutionizing Fibrosis Imaging: Unveiling Shear Wave Elastography for Small Animal Imaging

Non-Invasive Blood Pressure Measurement in Rodents: Considerations & Best Practices

Preeclampsia: From Hippocrates to Contemporary Research

Indirect Calorimetry for Rodent Research: New Approaches to Enhance Translational Value

Sympathetic Regulation in Human Pregnancy

Effects of Ovarian Failure on Muscle Form and Function

Mimicking the Ventricular Pressure-Volume Relationship Ex Vivo with Cardiac Slices

Deconstructing the Effects of Dietary Fat on Intestinal Cellular Networks

Metabolic Mechanisms that Contribute to Pregnancy-Induced Cardiac Growth and its Reversal

Clambake: An Algorithm to Decode Energy Expenditure Data from Metabolic Cages

Warming Up for Success: Comparative Efficacy of Thermoregulatory Devices in Rodent Anesthesia

Best Practices: Measuring Force, Resting Sarcomere Length, and Calcium in Cardiac Slice Preparations

Genetic and Hormonal Components of Sex Differences in Alzheimer's Disease

Visual Function with Aging in Normal and Alzheimer's Disease Model Mice

Getting to the Heart of Cardiovascular Research: From Yesterday to Today and Looking Towards Tomorrow

Applications of Humanized Mice in the Evaluation of Antibody-Drug Conjugates to Treat Autoimmune Diseases

Let's Get Physiological: Non-Invasive Intraoperative Monitoring Basics

Molecular Signals Mediating Increases in Muscle Size and Function

Photoacoustic Imaging in Angiotensin II Induced Cardiac Hypertrophy Mice

Preclinical Animal Models of IBD, GVHD, and Pulmonary Disease

Spatiotemporal Dynamics of Calcium and Neurotransmitters in Awake Mouse Models of Epilepsy

Functional Ultrasound Neuroimaging: Principles, Applications, & Perspectives

Unraveling European Animal Welfare Legislation for Biotech & Pharma

Next-Generation Safety Assessment Tools for Advancing In Vivo to In Vitro Translation

Superpixel Unmixing Algorithm from Micro to Macro Photoacoustic Imaging of Tissue Components

Understanding Animal Welfare Best Practices in Asia Pacific for Biotech & Pharma

Updates in Chronic Traumatic Encephalopathy (CTE)

Combined Near Infrared Photoacoustic Imaging and Ultrasound Detects Vulnerable Atherosclerotic Plaque

Developing a Novel Gene Therapy for Kcnv2 Retinopathy

Navigating Animal Welfare Legislation in North America: Insights for Biotech & Pharma

Compensatory Mechanisms in Parkinson's Disease

Calcium Signaling in Neurons and Glia in the Mouse Brain During Exploratory Behavior

Continuous Non-Invasive Hemodynamics Monitoring System for Humans: A Guide to Using the Finapres NOVA

The Heat is On: A Technical Overview of Animal Warming

Indwelling Portal Vascular Access Ports: Application, Advantages, and Management

Measuring Neuronal Activity and Vascular Physiology in the Human Brain Using High-Resolution Functional Magnetic Resonance Imaging

Advancing Disease Modeling for Drug Discovery by Modulating iPSCs with CRISPR and Neuronal Differentiation

More Than What You Eat: The Regulation of Metabolic Health and Aging by Diet Composition and Activity

Successful Modification of a Rodent Surgical Procedure and Device for Vascular Access in Minipigs (Vascular Access Button)

Understanding Advanced Cardiac Tissue Slice Applications

Control of Muscle Glucose Uptake in vivo: Thinking Outside the Myocyte

Cellular Brain Repair for Parkinson's Disease: Is the Answer in the (Biomaterial) Matrix?

Unveiling the Primate Brain: Advanced Insights through Ultra-Dense Electrophysiology

Systemic and Intraspinal Pathology and Repair After Spinal Cord Injury in Rodents

Monitoring Refractive Development in Mice to Investigate Mechanisms of Myopia

The Use of Vascular Access Buttons in Rabbits for PK/TK Studies

From Models to Heartbeats: Computational Design of Vagus Nerve Stimulation for Cardiac Health

Noninvasive Blood Pressure Monitoring Using Kent Scientific's CODA Systems

Implantable Circuit-Specific Treatments for Autonomic Dysfunction

Past, Present, and Future of the Columbus Instruments "CLAMS"

Evaluation of Novel Therapies Using Spontaneous Seizure Models

Cut and Paste of Myosin Binding Protein-C in Striated Muscles

Turning Innovative Features Into Practical Benefits Within the Buxco Nose-Only Rodent Inhalation System

Impact of Sleep and Circadian Disruption on Human Health and Disease Risk

Integrating Patient Engagement and Trainee Development in Pre-Clinical Research

New Horizons: Gonadotropin-Releasing Hormone and Cognition

Talking Real Science with Stella Goulopoulou

#ExpertAnswers: Andrew Gaffney and Erin Knock on Neural Progenitor Cell Differentiation

Talking Real Science with Oliver Wearing

#ExpertAnswers: Marcel Perret-Gentil on Improving Surgical Outcomes

Talking Real Science with Martin Young

#ExpertAnswers: Davide Boido and Antoine Bergel on Multimodal Neuroimaging

#ExpertAnswers: Jastyn P√∂pplau and Marilena Hnida on Prefrontal Networks

#ExpertAnswers: Artur Fedorowoski on Cardiovascular Dysautonomia in Post-COVID-19

Talking Real Science with Yelena Akelina

#ExpertAnswers: Connar Westgate on Intracranial Pressure Measurements

#ExpertAnswers: Audrey Dubourg and Gareth Guenigault on the Organ-On-A-Chip Approach

#ExpertAnswers: Sarah Greising on Muscle Injury Recovery

#ExpertAnswers: Dudley Lamming on the Influence of Sex and Genetic Background on Diet

#ExpertAnswers: Cole McLarty, Nick Glover, and Tim Hacker on Pressure-Volume Loops

#ExpertAnswers: George Portugal on Microelectrode Array Technology

#ExpertAnswers: Adrián Rodr√≠guez-Contreras and Barbara Lind on Neurovascular Coupling

Industry Insights with Chris Rand from Aurora Scientific

#ExpertAnswers: Aaron Phillips on Neural Hemodynamic Control

#ExpertAnswers: Matthew Sparks on Vascular-Tubular Crosstalk

Industry Insights with Amy Sheng on Nanobodies: An Important Tool for the Next Generation of Tumor Diagnostics and Therapeutics

Industry Insights with Trent Lund on the ANY-maze Operant Interface

Talking Real Science with Chris Perry

#ExpertAnswers: Valeria Fumagalli and Nancy Kouassi on the Syrian golden hamster model of COVID-19

#ExpertAnswers: Michael Long and Kari Hoffman on Electrophysiology

#ExpertAnswers: Guto Montezano on COVID-19 and the Endothelium

Industry Insights with Yuning Chen on Recombinant Proteins

#ExpertAnswers: Jason Rogers and De Wet Wolmarans on Rodent Behavior Models

#ExpertAnswers: Louise Parr-Brownlie and Conor Underwood on Optogenetic Stimulation

Talking Real Science with Aaron Phillips

#ExpertAnswers: Bin Xie on Drug Development for Immuno-Oncology

#ExpertAnswers: Junseok Son on Maternal Exercise and Neonatal Health in Mice

#ExpertAnswers: Danielle Senador and Cole McLarty on Biotelemetry

#ExpertAnswers: Fiona McBryde on Blood Pressure and Flow

#ExpertAnswers: Martin Young on Nutrient Intake Cycles and Metabolism

#ExpertAnswers: Jason Gardner on Nicotine and the Heart

#ExpertAnswers: Marc Reitman and Oksana Gavrilova on Thermal Physiology

#ExpertAnswers: Andrea Bonetto on the Musculoskeletal Complications of Cancer and its Treatments

#ExpertAnswers: Pierre Pouget and Serge Picaud on Functional Ultrasound Imaging

#ExpertAnswers: Caroline Wuyts on Pregnancy and Glucose

#ExpertAnswers: Joanna Hummer and Florie Le Prieult on cOFM for in vivo Cerebral Fluid Sampling

#ExpertAnswers: Yasaman Soudagar and Roshni Christo on Neuronal Calcium Imaging

#ExpertAnswers: Jonas Treebak and Alexander Bartelt on Metabolic Adaptations

#ExpertAnswers: Paul Marvar on Fear and Cardiovascular Disease

#ExpertAnswers: Stefano Gaburro and Brun Ulfhake on Aging Science

#ExpertAnswers: Xuebin Qin on Inflammation and Immunophysiology

#ExpertAnswers: Aileen King on Experimental Protocol

#ExpertAnswers: Anna Cavaccini & James Dooley on Sensorimotor Network Development

#ExpertAnswers: Rohan Jagirdar on Sleep and Alzheimer's Disease

#ExpertAnswers: Fiona Harrison on Early Alzheimer's Disease

#ExpertAnswers: Alexandra Lubin & Jason Otterstrom on Automated Microscopy

#ExpertAnswers: P Boon Lim and Melanie Dani on Autonomic Dysfunction in Long-COVID

#ExpertAnswers: Dudley Lamming on Aging Science

#ExpertAnswers: Christian Schnell on Pharmacology Studies in Oncology Research

#ExpertAnswers: Rizwan Qaisar & Matthew Borkowski on Aging Science

#ExpertAnswers: Barry Setlow on Substance Use and Decision Making

#ExpertAnswers: Andrea Benucci on Decision Making Behavior in Mice

#ExpertAnswers: Angel Moreno on Optogenetics and the Cardiac Autonomic System

#ExpertAnswers: Christopher Axelrod & Sander Kooijman on Rodent Models of Pharmacotherapy and Chronotherapy

#ExpertAnswers: Michael Czech on CRISPR-Enhanced Adipocyte Browning

#ExpertAnswers: Gilles Martin on Cellular Mechanisms Behind Alcohol Abuse and Binge Drinking Behavior

#ExpertAnswers: Thao Nguyen on In-Vivo Cardiac Electrophysiology

#ExpertAnswers: John Hasenau & Jeffrey Zynda on Animal Model Translation, Welfare and Housing

#ExpertAnswers: Lais Berro on the Behavioral Effects of Benzodiazepines

#ExpertAnswers: Alicia Brantley on Novel Object Tests

#ExpertAnswers: Brendan Dougherty on Sex Hormones and Neuroplasticity

#ExpertAnswers: Dee Silverthorn on Teaching Anatomy & Physiology

#ExpertAnswers: Julio Ayala & Matt Robinson on Stress, Exercise, Metabolism and Obesity

#ExpertAnswers: Scott Hall on Attention Deficit Hyperactivity Disorder (ADHD)

#ExpertAnswers: Simon Schultz & Michael Goard on Two-Photon Neuroimaging

#ExpertAnswers: Corina Bondi on Traumatic Brain Injury

#ExpertAnswers: Lauren Woodie and Matt Morris on Metabolism, Diet, & Energy Expenditure

#ExpertAnswers: Lior Bikovski & Shivang Sunil Parikh on Home Cage Monitoring Systems for Behavioral Research

#ExpertAnswers: Ricci Wesselink on Nursing Education

#ExpertAnswers: Robert Wykes & Anthony Umpierre on Studying Epilepsy Using Microscopy, Electrophysiology, and Optogenetics

#ExpertAnswers: Fred Beasley on Obesity

#ExpertAnswers: Sharon Ladyman & Vicki Vieira-Potter on Metabolic Phenotyping

#ExpertAnswers: Carl Petersen & Alexei Verkhratsky on Functional Neuroimaging

#ExpertAnswers: Katsu Funai on Obesity

#ExpertAnswers: Zhen Yan & Diego Bohórquez on Obesity

#ExpertAnswers: Chris Ward, Ramzi Khairallah & Sharon Hesterlee on Muscular Dystrophy

#ExpertAnswers: Artem Shatillo & Zsolt Lenkei on Functional Ultrasound Imaging

#ExpertAnswers: Ole Petersen, Roop Mallik & Erwin Neher on Endocytosis and Calcium Signaling in the Context of SARS-CoV-2

#ExpertAnswers: Marshall McCue on Stable Isotope Tracers in Preclinical Models of Obesity

#ExpertAnswers: Jennifer Petrosino & Chris Adams on VO2 Max

#ExpertAnswers: John Hasenau and Stefano Gaburro on Biosafety in Animal Modeling

#ExpertAnswers: DeWayne Townsend and Adam Goodwill on the Fundamentals of Pressure-Volume Loop Analysis

#ExpertAnswers: Miroslaw Janowski and Piotr Walczak on Imaging for Precision Medicine

#ExpertAnswers: Kaushikaram Subramanian & Volker Enzmann on the Optomotor Reflex

#ExpertAnswers: Tonya Coulthard on the Capabilities of PET/CT Imaging

#ExpertAnswers: Tim West & Matt Borkowski on Single Muscle Fiber Mechanics

#ExpertAnswers: Robert Gould and Michael Girand on Utilizing EEG to Study Sleep, Substance Use and CNS Disorders

#ExpertAnswers: John Cirrito & Candace Rhode-Johnson on Micro-dialysis and Neuroscience

#ExpertAnswers: Konrad Juczewski and Mary Ann Go on Place Cell Mapping and Stress Monitoring

#ExpertAnswers: Ralph Lydic and Tally Largent-Milnes on the Opioid Epidemic

#ExpertAnswers: Melanie White on Isolated Langendorff Heart Principles

#ExpertAnswers: Sarah Stuart, Jon Pacios-Filardo, Alexander Dityatev, Weilun Sun, and Norbert Hájos on Neurophysiology

#ExpertAnswers: Marcio Furtado on EEG Monitoring in the Study of Experimental Epilepsy

#ExpertAnswers: Tim Hacker on Models of Cardiovascular Disease in Rodents

#ExpertAnswers: Keshari Thakali and Aaron Stupica on Maternal Obesity Effects on Offspring

#ExpertAnswers: Clive May and Yugeesh Lankadeva on Measuring Tissue Perfusion